Volume 12 Issue 12
he Triglyceride Conundrum: Unraveling the Factors Affecting the Disparity Between Non-Fasting and Fasting Levels
1Dr. Fakhra Noureen, 2Dr Abeerah Zainub, 3Dr. Muhammad Yameen Mangan, 4Dr Atta Ullah, 5Dr. Nusrat Ali, 6Dr Muhammad Shuaib, 7Muhammad Kashif Habib, 8Nael Abdulrahman Rashed Aljaddoa, 8Kashif Lodhi
1Chemical Pathology, Akhtar saeed medical college Rawalpindi.
2Islamic İnternational Medical College Rawalpindi 3Gastroenterology, Shaheed Mohtarma Benazir Bhutto Medical College Lyari Karachi Sindh
4Community medicine, Mekran Medical college Turbat,
5HBS Medical n Dental College Islamabad,
6Department of Medicine, Mohiuddin Teaching Hospital, Mirpur AJK,
7Resident physician, medical c unit saidu group of teaching hospital swat,
8Pharmaceutical Science,Hail Health Cluster, Hail, Saudi Arabia,
9Department of Agricultural, Food and Environmental Sciences. Università Politécnica delle Marche Via Brecce Bianche 10, 60131 Ancona (AN) Italy,
Abstract
Objective: Little is known regarding the size of the difference in triglycerides between those who fast and those who don’t, or if this difference is influenced by certain possible risk factors for cardiovascular disease (CVD).
Methods: Between 2018 and 2023, an 8,073- participant cross-sectional research was done to examine the distinctions between non-fasting and fasting triglycerides and their possible correlation with risk factors for cardiovascular disease (CVD). According to whether or not they were fasting, participants were split into two groups. The variation between non-fasting and fasting triglycerides and their correlation with CVD riskvariables were estimated using linear regression models.
Results: After controlling for confounders, it was discovered that individuals who fasted had lower triglycerides than those who did not, with a difference of 4.22 mg/dL that was statistically significant. The presence of hypertension, the usage of antihyperlipidemic medications, and LDL cholesterol levels were observed to impact the difference in triglyceride levels between fasting and non-fasting. The difference was more pronounced in those with hypertension, antihyperlipidemic medication use, or levels of LDL cholesterol below 130 mg/dL.
Conclusions: The average sample showed a 4 mg/dL difference in triglycerides between non- fasting and fasting, and the presence of hypertension, the usage of antihyperlipidemic drugs, and LDL cholesterol levels all influenced the size of the changes. These findings may facilitate the accurate estimation of CVD risk utilising non- fasting and fasting triglycerides.
Keywords: Fasting, Triglyceride, Cardiovascular.
