Volume 11 Issue 3
Enhancing Data Completeness in Early Detection Pathway of Prostate Cancer: Integration of a Dashboard-Driven Feedback Tool to Improve Quality of Care
Lucas C. van Maaren,Nanne Aben,Jolien van Kesteren,Veerle M. D. Struben,Maarten Stals,Kurdo Barwari,Jana Stárková,Erik van Muilekom,Jeroen Visser,Arnoud W. Postema,Matthias F. van Alphen,Marinus J. Hagens,Thierry N. Boellaard,Stijn W. T. P. J. Heijmink,Margriet C. van Dijk-de Haan,Pim J. van Leeuwen andLaura S. Mertens
1Department of Pulmology, Special Hospital for Pulmonary Diseases, 10000 Zagreb, Croatia
2Department of Dermatovenereology, University Hospital Center Sestre Milosrdnice, 10000 Zagreb, Croatia
3School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia
4Department for Respiratory Infections, Dr. Fran Mihaljević University Hospital for Infections Diseases, 10000 Zagreb, Croatia
5Faculty of Dental Medicine and Health Osijek, 31000 Osijek, Croatia
6Department of Dental Medicine, University Hospital of Split, 21000 Split, Croatia
7Department of Oral Medicine, Study of Dental Medicine, School of Medicine, University of Split, 21000 Split, Croatia
8Department of Emergency Medicine, University Hospital Center Sestre Milosrdnice, 10000 Zagreb, Croatia
9Department of Clinical Chemistry, University Hospital Center Sestre Milosrdnice, 10000 Zagreb, Croatia
Author to whom correspondence should be addressed.
Abstract
Background/Objectives: The aim of this study is to investigate the effect on choroidal parameters of drug withdrawal in patients taking α1 adrenergic receptor antagonist (ARA) inhibitors. Methods: In total, 32 eyes of 32 patients under alpha-lytic therapy, and 32 eyes of 32 control subjects, both scheduled for cataract surgery in the fellow eye, were included. EDI-OCT was performed in all patients and subfoveal choroidal thickness (SFCT), luminal choroidal area (LCA), stromal choroidal area (SCA), total choroidal area (TCA), and choroidal vascularity index (CVI) during the preoperative visit were compared with data approximately 1 month after alpha-lytic withdrawal. The same assessments were performed in the control group. Results: SFCT and LCA were significantly reduced in the patients 1 month after alfa-lytic therapy withdrawal (p < 0.05), whereas in the control group, no changes in choroidal parameters were observed. Conclusions: The data proved that α1ARA inhibitors affected choroidal vessels, whereas no modification of choroidal stroma was observed.
Keywords: IFIS; choroid; choroidal thickness; CVI; cataract surgery; cataract; SFCT
